This study reveals that enhancing the activity of a conserved “housekeeping” gene can significantly elevate fruit nutritional and sensory traits. By increasing the expression of a tRNA-associated gene ...

Inside every cell, thousands of molecular signals collide, overlap, and compensate, obscuring the true drivers of gene ...

DNA is the blueprint of life. Genes encode proteins and serve as the body's basic components. However, building a functioning ...

Researchers developed e2MPRA, a high-throughput technique that simultaneously measures cis-regulatory element activity and ...

While African governments expand basic treatment, high-income countries adopt the first gene-editing therapy to cure sickle cell.

Daphne O. Martschenko and Sam Trejo both want to make the world a better, fairer, more equitable place. But they disagree on whether studying social genomics—elucidating any potential genetic ...

CRISPR gene therapy Casgevy can nearly eliminate sickle cell crises, but difficult stem‑cell collection is delaying access ...

Researchers identified three chromosome 21 genes that are overactive in brain cells of individuals with Down syndrome, and demonstrated partial molecular correction using antisense oligonucleotides.

A groundbreaking Alzheimer's study has developed a unique genetic map, revealing crucial insights into gene activity and potential disease-driving sequences in the brain.

As Uganda rolls out mandatory nationwide screening of newborns for sickle cell disease this month, a gene therapy celebrated in the United States and Europe remains financially out of reach for most ...

As Uganda rolls out mandatory nationwide screening of newborns for sickle cell disease this month, a gene therapy celebrated ...

It is really crazy to think about,' says 18-year-old Ty Sperle. 'We're definitely at a turning point in medicine' ...