DNA origami sounds like science fiction, but for HIV vaccine researchers it is becoming a practical design tool. By folding strands of DNA into tiny three-dimensional scaffolds, scientists can arrange ...

A new vaccine design uses folded DNA to steer the immune system toward producing the rare immune cells needed to make protective antibodies against HIV.

Practitioners of traditional origami can fold tiny, colorful bits of paper and make high art. But the growing group of scientists who practice DNA origami can fold genetic code itself, creating ...

Johns Hopkins engineers have created a new optical tool that could improve cancer imaging. Their approach, called SPECTRA, uses tiny nanoprobes that light up when they attach to aggressive cancer ...

A coarse-grained model of the DNA origami lilypad used in the study. The tails hanging down indicate where redox reporters are located. For scale, the diameter of the disk is approximately 80 nm.

New results provide a platform for more efficient, selective, and sensitive DNA biosensors that can be used in detecting various pathogens and diseases. Electrochemical DNA biosensors hold significant ...

DNA origami and beyond. A) DNA octahedron that inspired development of DNA origami. B) 2D DNA origami (smiley face serves as an example). C) Hollow 3D DNA origami shapes that are folded from 2D ...

DNA origami is a technique used for the nanoscale folding of DNA to develop two-dimensional (2D) and three-dimensional (3D) shapes at a nanoscale range. No bigger than a virus, each of these ...

Fluorogenic DNA aptamers produce light only in the correct structural state, enabling programmable molecular logic, biosensing, DNA origami integrity reporting, and reusable mRNA detection through ...