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'DNA origami' could be key for making an effective HIV vaccine, early study hints
A new vaccine design uses folded DNA to steer the immune system toward producing the rare immune cells needed to make ...
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DNA origami nanoparticles show early promise for future HIV vaccines
DNA origami sounds like science fiction, but for HIV vaccine researchers it is becoming a practical design tool. By folding strands of DNA into tiny three-dimensional scaffolds, scientists can arrange ...
Similarly to the artistic technique of folding paper into ornate shapes, DNA origami is a self-assembling technique of precisely folding single-stranded DNA scaffolds into well-defined nanostructures.
One of the biggest hurdles in developing an HIV vaccine is coaxing the body to produce the right kind of immune cells and ...
Johnson and Alistar competed as finalists in CU Boulder’s 2025 Lab Venture Challenge where their technology generated much interest from industry leaders. Access to DNA is crucial in many branches of ...
Essentially DNA origami enables long strands of DNA to fold, through self-assembly, into any desired shape. (In the 2006 paper, Rothemund famously used the technique to create miniature DNA smiley ...
The tiny motor could help spark research into future applications such as building molecular factories for useful chemicals or medical probes of molecules inside the bloodstream to detect diseases ...
A coarse-grained model of the DNA origami lilypad used in the study. The tails hanging down indicate where redox reporters are located. For scale, the diameter of the disk is approximately 80 nm.
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