Microtubules are cell constituents that display several astounding properties and a unique pattern of behavior during the cell cycle. Microtubules are regulated by several proteins and complexes, and ...

Certain chemotherapy drugs, including paclitaxel (Taxol), block cancer cell division by targeting microtubules—structural polymers that are critical for cell division and other functions. Such ...

Constructed with tubulin heterodimers connected into a hollow cylinder, the microtubule, an essential component of the ...

Microtubules function in concert with associated proteins that modify microtubule behavior and/or transmit signals that effect changes in growth. To better understand how microtubules and their ...

Patients with Parkinson's disease suffer a specific loss of dopaminergic neurons from the midbrain region that controls motor function. The exact mechanism of this selective neurodegeneration is ...

A physical dimension of a cell is seldom its Achilles' heel. Yet for the neurons that are affected in most kinds of peripheral neuropathy, it is the length of their axons that best accounts for their ...

Microtubules, a key component of the cytoskeleton in eukaryotic cells, serve as scaffolds and play vital roles in cellular processes such as cell division, cell migration, intracellular transport, and ...

Zachary Gergely, Ammon Crapo, Loren Hough, J. Richard McIntosh, and Meredith D. Betterton (2016). Molecular Biology of the Cell27, 3490. arXiv DOI: 1604.08134. DOI ...

The protein NEK7 regulates neuron formation, as it is required for dendrite growth and branching, as well as the formation and shaping of dendritic spines. The protein NEK7 regulates neuron formation, ...

The protein NEK7 regulates neuron formation, as it is required for dendrite growth and branching, as well as the formation and shaping of dendritic spines. These are the main conclusions of a study ...