Add Yahoo as a preferred source to see more of our stories on Google. Microglial receptor ADGRG1 helps immune cells eat amyloid plaques and may offer new hope for Alzheimer's treatment. (CREDIT: ...

As resident trash collectors, microglia survey the brain in search of detritus for disposal. How do they recognize the debris? In the case of plaques, a cell-surface receptor might be involved, though ...

Scientists discovered that lowering a specific molecule helps microglia switch into a protective state that quiets brain inflammation in Alzheimer’s. A small group of these cells seems to have an ...

Researchers have identified that microglia first help spread Alzheimer’s disease pathology across the brain and then activate to limit its neurodegenerative effects. Researchers from the VIB-KU Leuven ...

Tiny immune cells called microglia protect the central nervous system (CNS) in a multitude of ways: They provide innate immunity, shape neurodevelopment, maintain homeostasis and modulate neurological ...

When microglia wind up with a belly full of lipid droplets, it’s a sign that the cells are rallying, perhaps in vain, to a neurodegenerative threat. But according to a study published July 10 in Cell ...

Genetic neurodegenerative disorders like Tay-Sachs and Sandhoff disease currently have no effective treatments. A possible strategy is replacing affected cells with healthy ones in order to slow the ...

For years, researchers considered Alzheimer’s disease (AD) an amyloid beta and neuron-related condition. But having trained as a pathologist, Thomas Montine, who is now a neuropathology researcher at ...