A compact Cas12f nuclease shows high editing efficiency in human cells, with structural insights enabling an engineered variant potentially suited for future AAV‑compatible delivery.

The rapid evolution of CRISPR/Cas genome editing has redefined the possibilities of cellular and gene therapy, enabling ...

The publication, titled “ Comparative characterization of Cas12f orthologs reveals mechanistic features underlying enhanced genome editing efficiency” highlights the potential of MG119-28 (formally ...

In the first of a new series of GEN Keynote Webinars, Professor Rodolphe Barrangou, PhD (North Carolina State; EIC, The CRISPR Journal) offers a front-row perspective of the CRISPR revolution, the ...

The CRISPR-Cas gene-editing system has long been the focus of research as a promising tool in genome editing. However, the ...

Australian cancer researchers are the first to establish a next-generation gene-editing tool for modeling and interrogating human disease. A novel pre-clinical model expressing an enhanced version of ...

Our research focuses on two areas for precision gene and cell engineering: new tool development and AI-enabled engineering. First, we are moving beyond the current limitations of CRISPR-Cas9 by ...

The rapid evolution of CRISPR/Cas genome editing has redefined the possibilities of cellular and gene therapy, enabling precise correction ...

Colossal Biosciences is establishing standards for how biotechnology can responsibly support biodiversity conservation in an ...

New Rochelle, NY, October 22, 2024—An invited Guest Editorial entitled “Give Cas a Chance,” by Fyodor Urnov, PhD, Director of Technology & Translation at the Innovative Genomics Institute (IGI), ...