Adenosine diphosphate (ADP) or adenosine triphosphate (ATP)-containing important biological molecules can modify macromolecules like proteins and nucleic acids to alter their function in the cell.

We constructed a fluorescent sensor of adenylate nucleotides by combining a circularly permuted variant of GFP with a bacterial regulatory protein, GlnK1, from Methanococcus jannaschii. The sensor's ...

Researchers used a novel phosphate-activation reagent, 2-MeImIm-Cl, in an improved coupling reaction to increase the yield of ADP- or ATP-containing molecules. Unlike traditional reactions, the ...